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» Subspace Discovery for Promotion: A Cell Clustering Approach
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BMCBI
2007
152views more  BMCBI 2007»
13 years 5 months ago
Bioinformatic identification of novel putative photoreceptor specific cis-elements
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
Charles G. Danko, Vera A. McIlvain, Maochun Qin, B...
IMSCCS
2006
IEEE
13 years 11 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2007
123views more  BMCBI 2007»
13 years 5 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
RIAO
2007
13 years 6 months ago
Comprehensible and Accurate Cluster Labels in Text Clustering
The purpose of text clustering in information retrieval is to discover groups of semantically related documents. Accurate and comprehensible cluster descriptions (labels) let the ...
Jerzy Stefanowski, Dawid Weiss
ISBI
2008
IEEE
13 years 11 months ago
Unsupervised segmentation of cell nuclei using geometric models
Fluorescent microscopy of biological samples allows noninvasive screening of specific molecular events in-situ. This approach is useful for investigating intricate signalling path...
Shaun Fitch, Trevor Jackson, Peter Andras, Craig R...