11 search results - page 1 / 3 » Substitution Matrices and Mutual Information Approaches to M... |
LION
2009
Springer
13 years 11 months ago
2009
Springer
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classi cation are based on Blosum, P...
WICSA
2008
13 years 6 months ago
2008
Software modularization activities remain without the guidance of formal theories and models. According to Baldwin and Clark's [1] design rule theory (DRT) , modular architec...
BMCBI
2008
13 years 4 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
BMCBI
2004
13 years 4 months ago
2004
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
BIOSYSTEMS
2008
13 years 4 months ago
2008
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...