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BMCBI
2006
194views more  BMCBI 2006»
13 years 5 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
GECCO
2006
Springer
210views Optimization» more  GECCO 2006»
13 years 9 months ago
Clustering the heap in multi-threaded applications for improved garbage collection
Garbage collection can be a performance bottleneck in large distributed, multi-threaded applications. Applications may produce millions of objects during their lifetimes and may i...
Myra B. Cohen, Shiu Beng Kooi, Witawas Srisa-an
WSDM
2010
ACM
261views Data Mining» more  WSDM 2010»
14 years 2 months ago
Learning Similarity Metrics for Event Identification in Social Media
Social media sites (e.g., Flickr, YouTube, and Facebook) are a popular distribution outlet for users looking to share their experiences and interests on the Web. These sites host ...
Hila Becker, Mor Naaman, Luis Gravano
JKM
2010
131views more  JKM 2010»
13 years 3 months ago
Beyond the ba: managing enabling contexts in knowledge organizations
Purpose – Looking at the practical experience of organizations pursuing knowledge management, it is found that their efforts are primarily focused on creating the conditions and...
Chun Wei Choo, Rivadávia Correa Drummond de...