9 search results - page 1 / 2 » SuperDrug: a conformational drug database |
BIOINFORMATICS
2005
13 years 4 months ago
2005
BMCBI
2006
13 years 4 months ago
2006
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
NAR
2011
12 years 11 months ago
2011
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
NAR
2006
13 years 4 months ago
2006
Although tremendous effort has been put into synthetic libraries, most drugs on the market are still 10 natural compounds or derivatives thereof. There are encyclopaedias of natur...
JIB
2006
13 years 4 months ago
2006
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...