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» Support Vector Training of Protein Alignment Models
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NIPS
2001
13 years 6 months ago
Dynamic Time-Alignment Kernel in Support Vector Machine
A new class of Support Vector Machine (SVM) that is applicable to sequential-pattern recognition such as speech recognition is developed by incorporating an idea of non-linear tim...
Hiroshi Shimodaira, K.-I. Noma, Mitsuru Nakai, Shi...
BMCBI
2010
98views more  BMCBI 2010»
13 years 4 months ago
Learning to predict expression efficacy of vectors in recombinant protein production
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Wen-Ching Chan, Po-Huang Liang, Yan-Ping Shih, Uen...
BMCBI
2011
12 years 11 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...
BMCBI
2008
138views more  BMCBI 2008»
13 years 4 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2008
178views more  BMCBI 2008»
13 years 4 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...