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» Support vector machine learning from heterogeneous data: an ...
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JCB
2007
144views more  JCB 2007»
13 years 5 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2008
202views more  BMCBI 2008»
13 years 5 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
UAI
2003
13 years 7 months ago
On the Convergence of Bound Optimization Algorithms
Many practitioners who use EM and related algorithms complain that they are sometimes slow. When does this happen, and what can be done about it? In this paper, we study the gener...
Ruslan Salakhutdinov, Sam T. Roweis, Zoubin Ghahra...
BMCBI
2010
153views more  BMCBI 2010»
13 years 5 months ago
MimoSA: a system for minimotif annotation
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they a...
Jay Vyas, Ronald J. Nowling, Thomas Meusburger, Da...
SIGOPS
2010
162views more  SIGOPS 2010»
13 years 4 months ago
Visual and algorithmic tooling for system trace analysis: a case study
Despite advances in the application of automated statistical and machine learning techniques to system log and trace data there will always be a need for human analysis of machine...
Wim De Pauw, Steve Heisig