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» Syntenic Layout of Two Assemblies of Related Genomes
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BMCBI
2011
13 years 14 days ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
ESA
2001
Springer
105views Algorithms» more  ESA 2001»
13 years 10 months ago
SNPs Problems, Complexity, and Algorithms
Abstract. Single nucleotide polymorphisms (SNPs) are the most frequent form of human genetic variation. They are of fundamental importance for a variety of applications including m...
Giuseppe Lancia, Vineet Bafna, Sorin Istrail, Ross...
BMCBI
2010
148views more  BMCBI 2010»
13 years 5 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2010
93views more  BMCBI 2010»
13 years 5 months ago
JunctionViewer: customizable annotation software for repeat-rich genomic regions
Background: Repeat-rich regions such as centromeres receive less attention than their gene-rich euchromatic counterparts because the former are difficult to assemble and analyze. ...
Thomas K. Wolfgruber, Gernot G. Presting
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Automated simultaneous analysis phylogenetics (ASAP): an enabling tool for phlyogenomics
Background: The availability of sequences from whole genomes to reconstruct the tree of life has the potential to enable the development of phylogenomic hypotheses in ways that ha...
Indra Neil Sarkar, Mary G. Egan, Gloria M. Coruzzi...