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» Systematic calibration of a cell signaling network model
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BMCBI
2010
150views more  BMCBI 2010»
13 years 3 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
JCNS
2010
126views more  JCNS 2010»
13 years 2 months ago
Calibration of the head direction network: a role for symmetric angular head velocity cells
Abstract Continuous attractor networks require calibration. Computational models of the head direction (HD) system of the rat usually assume that the connections that maintain HD n...
Peter Stratton, Gordon Wyeth, Janet Wiles
BMCBI
2010
110views more  BMCBI 2010»
13 years 3 months ago
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
Haruna Imamura, Nozomu Yachie, Rintaro Saito, Yasu...
JCNS
2000
142views more  JCNS 2000»
13 years 3 months ago
A Temporal Mechanism for Generating the Phase Precession of Hippocampal Place Cells
The phase relationship between the activity of hippocampal place cells and the hippocampal theta rhythm systematically precesses as the animal runs through the region in an environ...
Amitabha Bose, Victoria Booth, Michael Recce
DATE
2008
IEEE
125views Hardware» more  DATE 2008»
13 years 10 months ago
Current source based standard cell model for accurate signal integrity and timing analysis
— The inductance and coupling effects in interconnects and non-linear receiver loads has resulted in complex input signals and output loads for gates in the modern deep submicron...
Amit Goel, Sarma B. K. Vrudhula