15 search results - page 2 / 3 » TAPPA: topological analysis of pathway phenotype association |
BMCBI
2007
13 years 5 months ago
2007
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
BMCBI
2005
13 years 5 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
BMCBI
2008
13 years 5 months ago
2008
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
BMCBI
2008
13 years 5 months ago
2008
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
BMCBI
2007
13 years 5 months ago
2007
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...