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» TOPOFIT-DB, a database of protein structural alignments base...
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BMCBI
2008
164views more  BMCBI 2008»
13 years 4 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2006
160views more  BMCBI 2006»
13 years 4 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2006
161views more  BMCBI 2006»
13 years 4 months ago
Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
Background: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or prote...
Alan Christoffels, Richard Bartfai, Hamsa Srinivas...