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BMCBI
2005
113views more  BMCBI 2005»
13 years 5 months ago
Alternative splicing and protein function
Background: Alternative splicing is a major mechanism of generating protein diversity in higher eukaryotes. Although at least half, and probably more, of mammalian genes are alter...
A. D. Neverov, Irena I. Artamonova, Ramil N. Nurtd...
ALMOB
2006
155views more  ALMOB 2006»
13 years 6 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
NIPS
2004
13 years 7 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
JIB
2006
78views more  JIB 2006»
13 years 6 months ago
Identification of embryo specific human isoforms using a database of predicted alternative splice forms
Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from a small number of genes. Its study became one of the hot ...
Heike Pospisil
BMCBI
2008
132views more  BMCBI 2008»
13 years 6 months ago
Exon level integration of proteomics and microarray data
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
Danny A. Bitton, Michal J. Okoniewski, Yvonne Conn...