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BMCBI
2010
99views more  BMCBI 2010»
13 years 5 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BMCBI
2008
146views more  BMCBI 2008»
13 years 5 months ago
EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries
Background: Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as U...
Robin P. Smith, William J. Buchser, Marcus B. Lemm...
BMCBI
2006
123views more  BMCBI 2006»
13 years 5 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2007
111views more  BMCBI 2007»
13 years 5 months ago
CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes
Background: The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequenc...
Gert Sclep, Joke Allemeersch, Robin Liechti, Bj&ou...
NAR
2010
143views more  NAR 2010»
12 years 12 months ago
WormBase: a comprehensive resource for nematode research
WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evo...
Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri...
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