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» The Statistical Significance of Max-Gap Clusters
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RECOMB
2004
Springer
14 years 4 months ago
The Statistical Significance of Max-Gap Clusters
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Rose Hoberman, David Sankoff, Dannie Durand
JCB
2008
170views more  JCB 2008»
13 years 4 months ago
Efficiently Identifying Max-Gap Clusters in Pairwise Genome Comparison
The spatial clustering of genes across different genomes has been used to study important problems in comparative genomics, from identification of operons to detection of homologo...
Xu Ling, Xin He, Dong Xin, Jiawei Han
BMCBI
2007
99views more  BMCBI 2007»
13 years 4 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
NIPS
2004
13 years 6 months ago
Detecting Significant Multidimensional Spatial Clusters
Assume a uniform, multidimensional grid of bivariate data, where each cell of the grid has a count ci and a baseline bi. Our goal is to find spatial regions (d-dimensional rectang...
Daniel B. Neill, Andrew W. Moore, Francisco Pereir...
BIOINFORMATICS
2006
89views more  BIOINFORMATICS 2006»
13 years 4 months ago
Maximum significance clustering of oligonucleotide microarrays
Affymetrix high-density oligonucleotide microarrays measure expression of DNA transcripts using probesets, i.e. multiple probes per transcript. Usually, these multiple measurement...
Dick de Ridder, Frank J. T. Staal, Jacques J. M. v...