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BIOINFORMATICS
2005
134views more  BIOINFORMATICS 2005»
13 years 5 months ago
Outcome signature genes in breast cancer: is there a unique set?
Motivation: direct bearing whose expres Sorlie et al., 2 gene sets is a diseases (Lossos et al., 2004; Miklos and Maleszka, 2004), and the variables that could account questions i...
Liat Ein-Dor, Itai Kela, Gad Getz, David Givol, Ey...
BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
SPRINT: A new parallel framework for R
Background: Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples. The analysis of t...
Jon Hill, Matthew Hambley, Thorsten Forster, Murie...
BMCBI
2010
114views more  BMCBI 2010»
13 years 5 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2005
88views more  BMCBI 2005»
13 years 5 months ago
Using large-scale perturbations in gene network reconstruction
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computatio...
Thomas MacCarthy, Andrew Pomiankowski, Robert Seym...
BMCBI
2010
193views more  BMCBI 2010»
13 years 23 days ago
Mayday - integrative analytics for expression data
Background: DNA Microarrays have become the standard method for large scale analyses of gene expression and epigenomics. The increasing complexity and inherent noisiness of the ge...
Florian Battke, Stephan Symons, Kay Nieselt