Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
We propose novel techniques for microarray image analysis. In particular, we describe an overall pipeline able to solve the most common problems of microarray image analysis. We pr...
Sebastiano Battiato, Gianpiero di Blasi, Giovanni ...
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
In this paper, we propose a new clustering procedure for high dimensional microarray data. Major difficulty in cluster analysis of microarray data is that the number of samples to ...