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    BMCBI
    2006
    175views more  BMCBI 2006»
    Parameter estimation for stiff equations of biosystems using radial basis function networks
    13 years 5 months ago
    Parameter estimation for stiff equations of biosystems using radial basis function networks
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    Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
    Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 5 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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