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BMCBI
2005
119views more  BMCBI 2005»
13 years 3 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
13 years 10 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
ISMB
1997
13 years 5 months ago
Hierarchical Protein Structure Superposition Using Both Secondary Structure and Atomic Representations
The structural comparison of proteins has become increasingly important as a means to identify protein motifs and fold families. In this paper we present a new algorithm for the c...
Amit Pal Singh, Douglas L. Brutlag
EC
2007
101views ECommerce» more  EC 2007»
13 years 3 months ago
Revisiting Negative Selection Algorithms
This paper reviews the progress of negative selection algorithms, an anomaly/change detection approach in Artificial Immune Systems (AIS). Following its initial model, we try to ...
Zhou Ji, Dipankar Dasgupta