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» The evolutionary capacity of protein structures
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BMCBI
2008
138views more  BMCBI 2008»
13 years 6 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
NAR
2000
120views more  NAR 2000»
13 years 5 months ago
SCOP: a Structural Classification of Proteins database
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classificati...
Loredana Lo Conte, Bart Ailey, Tim J. P. Hubbard, ...
GECCO
2005
Springer
119views Optimization» more  GECCO 2005»
13 years 11 months ago
A multi-objective evolutionary approach to peptide structure redesign and stabilization
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
Tim Hohm, Daniel Hoffmann
BMCBI
2011
13 years 25 days ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng