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» The greedy path-merging algorithm for sequence assembly
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RECOMB
2001
Springer
13 years 10 months ago
The greedy path-merging algorithm for sequence assembly
Two different approaches to determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly-funded Human Genome Proje...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
JCB
2000
105views more  JCB 2000»
13 years 5 months ago
A Greedy Algorithm for Aligning DNA Sequences
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic progra...
Zheng Zhang 0004, Scott Schwartz, Lukas Wagner, We...
JACM
2002
94views more  JACM 2002»
13 years 5 months ago
The greedy path-merging algorithm for contig scaffolding
Given a collection of contigs and mate-pairs. The Contig Scaffolding Problem is to order and orientate the given contigs in a manner that is consistent with as many mate-pairs as p...
Daniel H. Huson, Knut Reinert, Eugene W. Myers
CEC
2007
IEEE
13 years 9 months ago
Efficient assembling of genome fragments using genetic algorithm enhanced by heuristic search
Abstract-- Shotgun sequencing is the state-of-the-art to decode genome sequence. However this technique needs a lot of fragments. Combining those fragments correctly requires enorm...
Satoko Kikuchi, Goutam Chakraborty
ISMB
1998
13 years 6 months ago
Automated Clustering and Assembly of Large EST Collections
The avMlability of large EST(Expressed Sequence Tag)databases has led to a revolution in the waynew genes are cloned. Difficulties arise, however,due to high error rates and redun...
David P. Yee, Darrell Conklin