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BMCBI
2006
203views more  BMCBI 2006»
13 years 4 months ago
Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis dat
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Seon-Young Kim, YongSung Kim
HCI
2011
12 years 7 months ago
Acoustic Modeling of Dialogue Elements for Document Accessibility
Pepi Stavropoulou, Dimitris Spiliotopoulos, Georgi...
BMCBI
2007
147views more  BMCBI 2007»
13 years 4 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
BMCBI
2010
103views more  BMCBI 2010»
13 years 4 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
CONCURRENCY
2010
127views more  CONCURRENCY 2010»
13 years 4 months ago
Extreme scalability challenges in micro-finite element simulations of human bone
Coupling recent imaging capabilities with microstructural finite element (microFE) analysis offers a powerful tool to determine bone stiffness and strength. It shows high potentia...
Constantine Bekas, Alessandro Curioni, Peter Arben...