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BMCBI
2010
112views more  BMCBI 2010»
13 years 5 months ago
Computational identification of rare codons of Escherichia coli based on codon pairs preference
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
Xianming Wu, Songfeng Wu, Dong Li, Jiyang Zhang, L...
BMCBI
2008
109views more  BMCBI 2008»
13 years 5 months ago
Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis
Background: Correctly merged data sets that have been independently genotyped can increase statistical power in linkage and association studies. However, alleles from microsatelli...
Angela P. Presson, Eric M. Sobel, Paivi Pajukanta,...
BMCBI
2008
141views more  BMCBI 2008»
13 years 5 months ago
MiRTif: a support vector machine-based microRNA target interaction filter
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
Yuchen Yang, Yu-Ping Wang, Kuo-Bin Li
BMCBI
2006
104views more  BMCBI 2006»
13 years 5 months ago
SinicView: A visualization environment for comparisons of multiple nucleotide sequence alignment tools
Background: Deluged by the rate and complexity of completed genomic sequences, the need to align longer sequences becomes more urgent, and many more tools have thus been developed...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...
BMCBI
2006
82views more  BMCBI 2006»
13 years 5 months ago
Profiling alternatively spliced mRNA isoforms for prostate cancer classification
Background: Prostate cancer is one of the leading causes of cancer illness and death among men in the United States and world wide. There is an urgent need to discover good biomar...
Chaolin Zhang, Hai-Ri Li, Jian-Bing Fan, Jessica W...
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