Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Motivation: The issue of high dimensionality in microarray data has been, and remains, a hot topic in statistical and computational analysis. Efficient gene filtering and differen...