11 search results - page 2 / 3 » Thermodynamics of RNA-RNA Binding |
BMCBI
2010
13 years 5 months ago
2010
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
JCC
2011
13 years 17 days ago
2011
Abstract: With today’s available computer power, free energy calculations from equilibrium molecular dynamics simulations “via counting” become feasible for an increasing num...
BMCBI
2006
13 years 5 months ago
2006
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
BMCBI
2007
13 years 5 months ago
2007
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
BMCBI
2007
13 years 5 months ago
2007
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...