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BMCBI
2007
109views more  BMCBI 2007»
13 years 4 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2006
149views more  BMCBI 2006»
13 years 4 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2007
116views more  BMCBI 2007»
13 years 4 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...
ISMDA
2005
Springer
13 years 9 months ago
The Ontological Lens: Zooming in and out from Genomic to Clinical Level
Abstract. Ontology is the talk of the day in the medical informatics comm.unity. Its relevant role in the design and implementation of information systems in health care is now wid...
Domenico M. Pisanelli, Francesco Pinciroli, Marco ...
BMCBI
2010
144views more  BMCBI 2010»
13 years 4 months ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...