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» Transcriptional regulation at a glance
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BMCBI
2008
104views more  BMCBI 2008»
13 years 5 months ago
ExonMiner: Web service for analysis of GeneChip Exon array data
Background: Some splicing isoform-specific transcriptional regulations are related to disease. Therefore, detection of disease specific splice variations is the first step for fin...
Kazuyuki Numata, Ryo Yoshida, Masao Nagasaki, Ayum...
BMCBI
2005
145views more  BMCBI 2005»
13 years 5 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
13 years 5 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright
BMCBI
2008
90views more  BMCBI 2008»
13 years 5 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
JBCB
2007
161views more  JBCB 2007»
13 years 5 months ago
On Cooperative Quasi-Equilibrium Models of transcriptional Regulation
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...
Eric Mjolsness