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» Transforming Medicine: Genomics, Bioinformatics, and Human H...
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BMCBI
2006
149views more  BMCBI 2006»
13 years 5 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
BMCBI
2010
138views more  BMCBI 2010»
13 years 5 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2008
104views more  BMCBI 2008»
13 years 5 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
BIOINFORMATICS
2007
88views more  BIOINFORMATICS 2007»
13 years 5 months ago
Maximum likelihood of phylogenetic networks
Horizontal gene transfer (HGT) is believed to be ubiquitous among bacteria, and plays a major role in their genome diversiļ¬cation as well as their ability to develop resistance t...
Guohua Jin, Luay Nakhleh, Sagi Snir, Tamir Tuller
BMCBI
2006
192views more  BMCBI 2006»
13 years 5 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...