4 search results - page 1 / 1 » Two-part permutation tests for DNA methylation and microarra... |
BMCBI
2005
13 years 4 months ago
2005
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
BMCBI
2008
13 years 4 months ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
BMCBI
2010
13 years 4 months ago
2010
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
BMCBI
2007
13 years 4 months ago
2007
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...