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» Typing Aberrance in Signal Transduction
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ICNC
2005
Springer
13 years 10 months ago
Typing Aberrance in Signal Transduction
We have developed a calculus, called Ipi, for describing the aberrance in biological models. Our approach extends the traditional pi calculus to handle aberrant process in the sign...
Min Zhang, Guoqiang Li, Yuxi Fu, Zhizhou Zhang, Li...
CIS
2004
Springer
13 years 10 months ago
Representation of the Signal Transduction with Aberrance Using Ipi Calculus
The pi calculus has been applied to modelling biochemical networks. In these applications, the modelling is done without considerations to exceptions. The Ipi calculus, the Interfe...
Min Zhang, Guoqiang Li, Yuxi Fu, Zhizhou Zhang, Li...
BMCBI
2010
107views more  BMCBI 2010»
13 years 4 months ago
Conditional random pattern model for copy number aberration detection
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
Fuhai Li, Xiaobo Zhou, Wanting Huang, Chung-Che Ch...
BMCBI
2011
12 years 8 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BMCBI
2010
103views more  BMCBI 2010»
13 years 4 months ago
PostMod: sequence based prediction of kinase-specific phosphorylation sites with indirect relationship
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
Inkyung Jung, Akihisa Matsuyama, Minoru Yoshida, D...