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» UTR Reconstruction and Analysis Using Genomically Aligned ES...
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BMCBI
2006
143views more  BMCBI 2006»
13 years 5 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
NAR
2000
117views more  NAR 2000»
13 years 5 months ago
The TIGR Gene Indices: reconstruction and representation of expressed gene sequences
Expressed sequence tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence dat...
John Quackenbush, Feng Liang, Ingeborg Holt, Geo P...
BMCBI
2007
183views more  BMCBI 2007»
13 years 5 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
ICCS
2005
Springer
13 years 11 months ago
SWAT: A New Spliced Alignment Tool Tailored for Handling More Sequencing Errors
Abstract. There are several computer programs that align mRNA with its genomic counterpart to determine exon boundaries. Though most of these programs perform such alignment effici...
Yifeng Li, Hesham H. Ali
BMCBI
2011
12 years 9 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...