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TPDS
2002
75views more  TPDS 2002»
13 years 5 months ago
An Experimental Evaluation of I/O Optimizations on Different Applications
Many large scale applications have significant I/O requirements as well as computational and memory requirements. Unfortunately, the limited number of I/O nodes provided in a typic...
Meenakshi A. Kandaswamy, Mahmut T. Kandemir, Alok ...
BMCBI
2011
13 years 10 days ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
BMCBI
2011
12 years 11 months ago
The PathOlogist: An Automated Tool for Pathway-Centric Analysis
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
CCE
2011
12 years 11 months ago
Computational energy-based redesign of robust proteins
The robustness of a system is a property that pervades all aspects of Nature. The ability of a system to adapt itself to perturbations due to internal and external agents, to agin...
Giovanni Stracquadanio, Giuseppe Nicosia
BMCBI
2011
12 years 9 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...