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BMCBI
2011
12 years 8 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
BMCBI
2011
12 years 8 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
EUROSYS
2007
ACM
14 years 2 months ago
Adaptive control of virtualized resources in utility computing environments
Data centers are often under-utilized due to over-provisioning as well as time-varying resource demands of typical enterprise applications. One approach to increase resource utili...
Pradeep Padala, Kang G. Shin, Xiaoyun Zhu, Mustafa...
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
13 years 11 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...
BMCBI
2011
12 years 8 months ago
A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...
Juan R. González, Benjamin Rodriguez-Santia...
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