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BMCBI
2008
96views more  BMCBI 2008»
13 years 5 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2005
169views more  BMCBI 2005»
13 years 4 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
ACIIDS
2010
IEEE
170views Database» more  ACIIDS 2010»
13 years 2 months ago
On the Effectiveness of Gene Selection for Microarray Classification Methods
Microarray data usually contains a high level of noisy gene data, the noisy gene data include incorrect, noise and irrelevant genes. Before Microarray data classification takes pla...
Zhongwei Zhang, Jiuyong Li, Hong Hu, Hong Zhou
BMCBI
2010
108views more  BMCBI 2010»
12 years 12 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...
BMCBI
2010
153views more  BMCBI 2010»
13 years 5 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...