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BMCBI
2010
196views more  BMCBI 2010»
13 years 2 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
BMCBI
2008
133views more  BMCBI 2008»
13 years 5 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
KDD
2012
ACM
243views Data Mining» more  KDD 2012»
11 years 8 months ago
Storytelling in entity networks to support intelligence analysts
Intelligence analysts grapple with many challenges, chief among them is the need for software support in storytelling, i.e., automatically ‘connecting the dots’ between dispar...
M. Shahriar Hossain, Patrick Butler, Arnold P. Boe...
GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
13 years 11 months ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
BMCBI
2005
108views more  BMCBI 2005»
13 years 5 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...