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» Using sampling methods to improve binding site predictions
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ESANN
2006
13 years 6 months ago
Using sampling methods to improve binding site predictions
Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. In previous work we combine random selection under-sampling with th...
Yi Sun, Mark Robinson, Rod Adams, Rene te Boekhors...
ICANNGA
2007
Springer
149views Algorithms» more  ICANNGA 2007»
13 years 11 months ago
Using Real-Valued Meta Classifiers to Integrate and Contextualize Binding Site Predictions
Currently the best algorithms for transcription factor binding site predictions are severely limited in accuracy. However, a non-linear combination of these algorithms could improv...
Mark Robinson, Offer Sharabi, Yi Sun, Rod Adams, R...
BMCBI
2004
93views more  BMCBI 2004»
13 years 4 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2008
134views more  BMCBI 2008»
13 years 4 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
BMCBI
2010
121views more  BMCBI 2010»
13 years 4 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...