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WOB
2007
116views Bioinformatics» more  WOB 2007»
13 years 5 months ago
Validating Gene Clusterings by Selecting Informative Gene Ontology Terms with Mutual Information
Abstract. We propose a method for global validation of gene clusterings. The method selects a set of informative and non-redundant GO terms through an exploration of the Gene Ontol...
Ivan G. Costa, Marcílio Carlos Pereira de S...
BMCBI
2006
165views more  BMCBI 2006»
13 years 4 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
ICASSP
2008
IEEE
13 years 10 months ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
WABI
2005
Springer
179views Bioinformatics» more  WABI 2005»
13 years 9 months ago
Spectral Clustering Gene Ontology Terms to Group Genes by Function
Abstract. With the invention of biotechnological high throughput methods like DNA microarrays, biologists are capable of producing huge amounts of data. During the analysis of such...
Nora Speer, Christian Spieth, Andreas Zell
JIPS
2007
134views more  JIPS 2007»
13 years 4 months ago
An Efficient Functional Analysis Method for Micro-array Data Using Gene Ontology
: Microarray data includes tens of thousands of gene expressions simultaneously, so it can be effectively used in identifying the phenotypes of diseases. However, the retrieval of ...
Dong-wan Hong, Jong-keun Lee, Sung-soo Park, Sang-...