Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
Mining microarray gene expression data is an important research topic in bioinformatics with broad applications. While most of the previous studies focus on clustering either gene...
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Clustering for the analysis of the gene expression profiles has been used for identifying the functions of the genes and of unknown genes. Since the genes usually belong to multipl...
In this paper, a new method for evaluating the quality of clustering of genes is proposed based on mutual information criterion. Instead of using the conventional histogram-based ...