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BMCBI
2006
165views more  BMCBI 2006»
10 years 1 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
ICASSP
2008
IEEE
10 years 7 months ago
Probabilistic framework for gene expression clustering validation based on gene ontology and graph theory
Based on the correlation between expression and ontologydriven gene similarity, we incorporate functional annotations into gene expression clustering validation. A probabilistic f...
Yinyin Yuan, Chang-Tsun Li
BIBE
2010
IEEE
148views Bioinformatics» more  BIBE 2010»
9 years 8 months ago
Prediction of Gene Ontology Annotations Based on Gene Functional Clustering
We propose an algorithm that predicts potentially missing Gene Ontology annotations, in order to speed up the time-consuming annotation curation process. The proposed method extend...
Marco Tagliasacchi, Roberto Sarati, Marco Masserol...
BMCBI
2007
168views more  BMCBI 2007»
10 years 1 months ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
ICDM
2005
IEEE
215views Data Mining» more  ICDM 2005»
10 years 7 months ago
CLUGO: A Clustering Algorithm for Automated Functional Annotations Based on Gene Ontology
We address the issue of providing highly informative and comprehensive annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a...
In-Yee Lee, Jan-Ming Ho, Ming-Syan Chen
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