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BMCBI
2011
12 years 11 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
JUCS
2010
109views more  JUCS 2010»
12 years 12 months ago
Semantics of Query-Driven Communication of Exact Values
: We address the question of how to communicate among distributed processes values such as real numbers, continuous functions and geometrical solids with arbitrary precision, yet e...
Michal Konecný, Amin Farjudian
IEEEPACT
2003
IEEE
13 years 10 months ago
Reducing Datapath Energy through the Isolation of Short-Lived Operands
We present a technique for reducing the power dissipation in the course of writebacks and committments in a datapath that uses a dedicated architectural register file (ARF) to hol...
Dmitry Ponomarev, Gurhan Kucuk, Oguz Ergin, Kanad ...
MICCAI
2003
Springer
14 years 6 months ago
Determination of the Mechanical Properties of Soft Human Tissues through Aspiration Experiments
Mechanical models for soft human organs are necessary for a variety of medical applications, such as surgical planning, virtual reality surgery simulators, and for diagnostic purpo...
Alessandro Nava, Edoardo Mazza, Frederic Kleinerma...
DGO
2011
247views Education» more  DGO 2011»
12 years 4 months ago
Open government and e-government: democratic challenges from a public value perspective
We consider open government (OG) within the context of egovernment and its broader implications for the future of public administration. We argue that the current US Administratio...
Teresa M. Harrison, Santiago Guerrero, G. Brian Bu...