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» VarDetect: a nucleotide sequence variation exploratory tool
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BMCBI
2008
158views more  BMCBI 2008»
13 years 4 months ago
VarDetect: a nucleotide sequence variation exploratory tool
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Chumpol Ngamphiw, Supasak Kulawonganunchai, Anunch...
BMCBI
2011
12 years 8 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
BMCBI
2006
113views more  BMCBI 2006»
13 years 4 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
BMCBI
2010
143views more  BMCBI 2010»
13 years 2 months ago
A genome alignment algorithm based on compression
Background: Traditional genome alignment methods consider sequence alignment as a variation of the string edit distance problem, and perform alignment by matching characters of th...
Minh Duc Cao, Trevor I. Dix, Lloyd Allison
BMCBI
2006
132views more  BMCBI 2006»
13 years 4 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas