15 search results - page 1 / 3 » Variation in structural location and amino acid conservation... |
BMCBI
2005
13 years 5 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
BMCBI
2006
13 years 5 months ago
2006
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
BMCBI
2005
13 years 5 months ago
2005
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
BMCBI
2008
13 years 5 months ago
2008
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
BMCBI
2007
13 years 5 months ago
2007
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...