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» Variation in structural location and amino acid conservation...
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NAR
2006
98views more  NAR 2006»
13 years 5 months ago
dbPTM: an information repository of protein post-translational modification
ACT dbPTM is a database that compiles information on protein post-translational modifications (PTMs), such as the catalytic sites, solvent accessibility of amino acid residues, pro...
Tzong-Yi Lee, Hsien-Da Huang, Jui-Hung Hung, Hsi-Y...
BMCBI
2008
114views more  BMCBI 2008»
13 years 5 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2004
102views more  BMCBI 2004»
13 years 5 months ago
No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...
TCBB
2008
126views more  TCBB 2008»
13 years 5 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
ALMOB
2006
138views more  ALMOB 2006»
13 years 5 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh