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BMCBI
2008
96views more  BMCBI 2008»
13 years 5 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2008
115views more  BMCBI 2008»
13 years 5 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
BMCBI
2005
122views more  BMCBI 2005»
13 years 5 months ago
GenClust: A genetic algorithm for clustering gene expression data
Background: Clustering is a key step in the analysis of gene expression data, and in fact, many classical clustering algorithms are used, or more innovative ones have been designe...
Vito Di Gesù, Raffaele Giancarlo, Giosu&egr...
BMCBI
2004
150views more  BMCBI 2004»
13 years 5 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2005
145views more  BMCBI 2005»
13 years 5 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang