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BMCBI
2010
106views more  BMCBI 2010»
13 years 5 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2008
134views more  BMCBI 2008»
13 years 5 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...
BMCBI
2008
100views more  BMCBI 2008»
13 years 5 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
BMCBI
2005
85views more  BMCBI 2005»
13 years 5 months ago
Prediction of twin-arginine signal peptides
Background: Proteins carrying twin-arginine (Tat) signal peptides are exported into the periplasmic compartment or extracellular environment independently of the classical Secdepe...
Jannick Dyrløv Bendtsen, Henrik Nielsen, Da...
BMCBI
2010
165views more  BMCBI 2010»
13 years 5 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...