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BMCBI
2011
12 years 9 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
BMCBI
2006
95views more  BMCBI 2006»
13 years 5 months ago
Discrete profile comparison using information bottleneck
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
SIGMOD
2010
ACM
208views Database» more  SIGMOD 2010»
13 years 4 months ago
An automated, yet interactive and portable DB designer
Tuning tools attempt to configure a database to achieve optimal performance for a given workload. Selecting an optimal set of physical structures is computationally hard since it ...
Ioannis Alagiannis, Debabrata Dash, Karl Schnaitte...