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JCB
2000
103views more  JCB 2000»
13 years 4 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
BMCBI
2006
103views more  BMCBI 2006»
13 years 4 months ago
Improving missing value imputation of microarray data by using spot quality weights
Background: Microarray technology has become popular for gene expression profiling, and many analysis tools have been developed for data interpretation. Most of these tools requir...
Peter Johansson, Jari Häkkinen
BMCBI
2006
119views more  BMCBI 2006»
13 years 4 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2011
12 years 8 months ago
Evaluating methods for ranking differentially expressed genes applied to MicroArray Quality Control data
Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
Koji Kadota, Kentaro Shimizu