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BMCBI
2011
13 years 8 days ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
FCCM
2011
IEEE
220views VLSI» more  FCCM 2011»
12 years 9 months ago
Reducing the Energy Cost of Irregular Code Bases in Soft Processor Systems
— This paper describes an architecture and FPGA synthesis toolchain for building specialized, energy-saving coprocessors called Irregular Code Energy Reducers (ICERs) for a wide ...
Manish Arora, Jack Sampson, Nathan Goulding-Hotta,...
CHI
2011
ACM
12 years 9 months ago
PaperPhone: understanding the use of bend gestures in mobile devices with flexible electronic paper displays
Flexible displays potentially allow for interaction styles that resemble those used in paper documents. Bending the display, e.g., to page forward, shows particular promise as an ...
Byron Lahey, Audrey Girouard, Winslow Burleson, Ro...
PVLDB
2011
12 years 8 months ago
Merging What's Cracked, Cracking What's Merged: Adaptive Indexing in Main-Memory Column-Stores
Adaptive indexing is characterized by the partial creation and refinement of the index as side effects of query execution. Dynamic or shifting workloads may benefit from prelimi...
Stratos Idreos, Stefan Manegold, Harumi A. Kuno, G...
VEE
2012
ACM
255views Virtualization» more  VEE 2012»
12 years 1 months ago
Adding dynamically-typed language support to a statically-typed language compiler: performance evaluation, analysis, and tradeof
Applications written in dynamically typed scripting languages are increasingly popular for Web software development. Even on the server side, programmers are using dynamically typ...
Kazuaki Ishizaki, Takeshi Ogasawara, José G...