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ALMOB
2006
80views more  ALMOB 2006»
13 years 5 months ago
Effective p-value computations using Finite Markov Chain Imbedding (FMCI): application to local score and to pattern statistics
The technique of Finite Markov Chain Imbedding (FMCI) is a classical approach to complex combinatorial problems related to sequences. In order to get efficient algorithms, it is k...
Grégory Nuel
ALMOB
2006
80views more  ALMOB 2006»
13 years 5 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel
ALMOB
2006
138views more  ALMOB 2006»
13 years 5 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
ALMOB
2006
102views more  ALMOB 2006»
13 years 5 months ago
Mining, compressing and classifying with extensible motifs
Background: Motif patterns of maximal saturation emerged originally in contexts of pattern discovery in biomolecular sequences and have recently proven a valuable notion also in t...
Alberto Apostolico, Matteo Comin, Laxmi Parida
ALMOB
2006
110views more  ALMOB 2006»
13 years 5 months ago
New journal: Algorithms for Molecular Biology
This editorial announces Algorithms for Molecular Biology, a new online open access journal published by BioMed Central. By launching the first open access journal on algorithmic ...
Burkhard Morgenstern, Peter F. Stadler