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ALMOB
2006
106views more  ALMOB 2006»
13 years 5 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
ALMOB
2006
113views more  ALMOB 2006»
13 years 5 months ago
Inverse bifurcation analysis: application to simple gene systems
Background: Bifurcation analysis has proven to be a powerful method for understanding the qualitative behavior of gene regulatory networks. In addition to the more traditional for...
James Lu, Heinz W. Engl, Peter Schuster
ALMOB
2006
155views more  ALMOB 2006»
13 years 5 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
ALMOB
2007
155views more  ALMOB 2007»
13 years 5 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
ALMOB
2007
129views more  ALMOB 2007»
13 years 5 months ago
Consistency of the Neighbor-Net Algorithm
Background: Neighbor-Net is a novel method for phylogenetic analysis that is currently being widely used in areas such as virology, bacteriology, and plant evolution. Given an inp...
David Bryant, Vincent Moulton, Andreas Spillner