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BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BIBE
2005
IEEE
115views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
GOMIT: A Generic and Adaptive Annotation Algorithm Based on Gene Ontology Term Distributions
We address the issue of providing highly informative annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a set of candidate ...
In-Yee Lee, Jan-Ming Ho, Ming-Syan Chen
BIBE
2005
IEEE
116views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Stochastic Model of Protease-Ligand Reactions
Prediction of protein tertiary structure based on amino acid sequence is one of the most challenging open questions in computational molecular biology. The two most common experim...
Paul E. Anderson, Douglas W. Raiford, Deacon J. Sw...
BIBE
2005
IEEE
107views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
DSIM: A Distance-Based Indexing Method for Genomic Sequences
In this paper, we propose a Distance-based Sequence Indexing Method (DSIM) for indexing and searching genome databases. Borrowing the idea of video compression, we compress the ge...
Xia Cao, Beng Chin Ooi, HweeHwa Pang, Kian-Lee Tan...