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BMCBI
2011
12 years 8 months ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
BMCBI
2006
134views more  BMCBI 2006»
13 years 5 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2006
181views more  BMCBI 2006»
13 years 5 months ago
The comprehensive updated regulatory network of Escherichia coli K-12
Background: Escherichia coli is the model organism for which our knowledge of its regulatory network is the most extensive. Over the last few years, our project has been collectin...
Heladia Salgado, Alberto Santos-Zavaleta, Socorro ...
BMCBI
2006
89views more  BMCBI 2006»
13 years 5 months ago
SPODOBASE : an EST database for the lepidopteran crop pest Spodoptera
Background: The Lepidoptera Spodoptera frugiperda is a pest which causes widespread economic damage on a variety of crop plants. It is also well known through its famous Sf9 cell ...
Vincent Nègre, Thierry Hotelier, Anne-Natha...